Fellow Physician
University of Pennsylvania
Philadelphia, Pennsylvania
Matthew Ho, MB BCh BAO, PhD is a final-year hematology and oncology fellow and postdoctoral research fellow at the University of Pennsylvania, where he trains under the mentorship of Drs. Joseph Fraietta, Marco Ruella, Adam Cohen, and Alfred Garfall. He earned his medical degree from University College Dublin in Ireland and completed his Ph.D. at Dana-Farber Cancer Institute in Boston, MA, under the guidance of Drs. Giada Bianchi, Kenneth Anderson, and Peter O’Gorman. His doctoral research focused on interrogating the signaling pathways within the multiple myeloma (MM) bone marrow microenvironment that promote tumor survival and treatment resistance. He completed his internal medicine residency at the Mayo Clinic in Rochester, MN, where he received further research mentorship from Dr. Shaji Kumar.
Dr. Ho’s current research interests are twofold: (1) investigating the mechanisms underlying toxicities associated with BCMA-directed CAR T-cell therapy, and (2) developing next-generation CAR T-cell therapies with enhanced safety and durable efficacy in MM.
He has authored or co-authored over 75 peer-reviewed manuscripts, book chapters, and scientific abstracts. His work has been recognized with numerous honors, including research scholarships from the Wellcome Trust and the Mater Institute of Research & Therapy, ASH Abstract Achievement Awards, the Gold Humanism and Excellence in Teaching Award, and the Mayo Clinic Internal Medicine Residency’s Best Resident Educator and Outstanding Achievement in Research Awards.
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(OA-04) CD4+ T-Cells Mediate Immune-Related Adverse Events (CirAE) Following BCMA CAR-T Therapy
Thursday, September 18, 2025
16:30 - 16:40 East Coast USA Time