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    22nd International Myeloma Society Annual Meeting
    Oral Abstract

    Abstract Session 12

    Saturday, September 20, 2025
    11:00 - 11:50 East Coast USA Time
    Location: Room 718

    Presentations:

    • 11:00 - 11:10 East Coast USA Time
      (OA-37) Novel NKp30-directed Bispecific Natural Killer Cell Engagers Targeting GPRC5D or CD38 for the Treatment of Multiple Myeloma

      Abstract Presenter: Dorothee Winterberg, PhD (she/her/hers) – University Medical Center Schleswig-Holstein

    • 11:10 - 11:20 East Coast USA Time
      (OA-40) A Novel Dual Proteasome and HDAC6 Inhibitor I3MV-8b Potentiates Anti-CD38 Monoclonal Antibody Efficacy in Multiple Myeloma

      Abstract Presenter: Lanting Liu, MD – State Key Laboratory of Experimental Hematology; National Clinical Research Center for Blood Diseases;Haihe Laboratory of Cell Ecosystem; Institute of Hematology & Blood Diseases Hospital; Chinese Academy of Medical Sciences & Peking Union Medical College

    • 11:20 - 11:30 East Coast USA Time
      (OA-39) Targeting PHF19 Inhibits Myeloma progression and Increases IMiDs Sensitivity by Epigenetically Regulating MYC and IRF4 Pathway

      Abstract Presenter: Xiyue Sun, PhD student (she/her/hers) – State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.

    • 11:30 - 11:40 East Coast USA Time
      (OA-34) Exploring Molecular Glues to Activate Proteasomes and Develop Shared and Personalized Neoantigen-Based Therapeutics in Multiple Myeloma

      Abstract Presenter: James J. Driscoll, MD, PhD (he/him/his) – Case Western Reserve University

    • 11:40 - 11:50 East Coast USA Time
      (OA-64) Evidence for Pre-Existing Myeloma Cells with a Gene Expression Pattern Associated with Resistance to BCMA CAR T Cells.

      Abstract Presenter: Lawrence H. Boise, PhD – Emory University